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Mensajes - Cadavre Exquis

en: Hoy a las 08:05:49 1 General / The Big Picture / Re:STEM

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Cut In Ship Pollution Sparked Global Heating Spurt
Posted by BeauHD on Thursday May 30, 2024 @11:30PM from the termination-shock dept.

An anonymous reader quotes a report from The Guardian:
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The slashing of pollution from shipping in 2020 led to a big "termination shock" that is estimated have pushed the rate of global heating to double the long-term average, according to research. Until 2020, global shipping used dirty, high-sulphur fuels that produced air pollution. The pollution particles blocked sunlight and helped form more clouds, thereby curbing global heating. But new regulations at the start of 2020 slashed the sulphur content of fuels by more than 80%. The new analysis calculates that the subsequent drop in pollution particles has significantly increased the amount of heat being trapped at the Earth's surface that drives the climate crisis. The researchers said the sharp ending of decades of shipping pollution was an inadvertent geoengineering experiment, revealing new information about its effectiveness and risks.

Dr Tianle Yuan, at the University of Maryland, US, who led the study, said the estimated 0.2 watts per sq meter of additional heat trapped over the oceans after the pollution cut was "a big number, and it happened in one year, so it's a big shock to the system." "We will experience about double the warming rate compared to the long-term average" since 1880 as a result, he said. The heating effect of the pollution cut is expected to last about seven years. The research, published in the journal Communications Earth & Environment, combined satellite observations of sulphur pollution and computer modeling to calculate the impact of the cut. It found the short-term shock was equivalent to 80% of the total extra heating the planet has seen since 2020 from longer-term factors such as rising fossil-fuel emissions.

The scientists used relatively simple climate models to estimate how much this would drive up average global temperatures at the surface of the Earth, finding a rise of about 0.16C over seven years. This is a large rise and the same margin by which 2023 beat the temperature record compared with the previous hottest year. However, other scientists think the temperature impact of the pollution cut will be significantly lower due to feedbacks in the climate system, which are included in the most sophisticated climate models. The results of this type of analysis are expected later in 2024. [...] The new analysis indicates that this type of geoengineering would reduce temperatures, but would also bring serious risks. These include the sharp temperature rise when the pumping of aerosols stopped -- the termination shock -- and also potential changes to global precipitation patterns, which could disrupt the monsoon rains that billions of people depend on.
"We should definitely do research on this, because it's a tool for situations where we really want to cool down the Earth temporarily," like an emergency brake, said Dr Gavin Schmidt, Director of the NASA Goddard Institute for Space Studies. "But this is not going to be a long-term solution, because it doesn't address the root cause of global warming," which is emissions from fossil fuel burning.
Saludos.

en: Hoy a las 07:06:08 2 General / The Big Picture / Re:STEM

https://www.engadget.com/the-worlds-first-tooth-regrowing-drug-has-been-approved-for-human-trials-174423381.html

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The world’s first tooth-regrowing drug has been approved for human trials
If things go as planned, the medicine could be available to consumers by 2030.

Lawrence Bonk · 2024.05.30

Unsplash / Marek Studzinski

I remember being a kid and seeing my grandmother without her dentures for the first time. It was a harrowing experience. Now my dad has dentures so, genetically speaking, I’m several decades out from needing some myself. However, it’s possible that modern medicine will solve the issue of lost teeth by then, thanks to a new drug that's about to enter human trials.

The medicine quite literally regrows teeth and was developed by a team of Japanese researchers, as reported by New Atlas. The research has been led by Katsu Takahashi, head of dentistry and oral surgery at Kitano Hospital. The intravenous drug deactivates the uterine sensitization-associated gene-1 (USAG-1) protein that suppresses tooth growth. Blocking USAG-1 from interacting with other proteins triggers bone growth and, voila, you got yourself some brand-new chompers. Pretty cool, right?


Human trials start in September, but the drug has been highly successful when treating ferrets and mice and did its job with no serious side effects. Of course, the usual caveat applies. Humans are not mice or ferrets, though researchers seem confident that it’ll work on homo sapiens. This is due to a 97 percent similarity in how the USAG-1 protein works when comparing humans to other species.

September’s clinical trial will include adults who are missing at least one molar but there’s a secondary trial coming aimed at children aged two to seven. The kids in the second trial will all be missing at least four teeth due to congenital tooth deficiency. Finally, a third trial will focus on older adults who are missing “one to five permanent teeth due to environmental factors.”


Takahashi and his fellow researchers are so optimistic about this drug that they predict the medicine will be available for everyday consumers by 2030. So in six years we can throw our toothbrushes away and eat candy bars all day and all night without a care in the world (don’t actually do that.)

While this is the first drug that can fully regrow missing teeth, the science behind it builds on top of years of related research. Takahashi, after all, has been working on this since 2005. Recent advancements in the field include regenerative tooth fillings to repair diseased teeth and stem cell technology to regrow the dental tissue of children.
Saludos.
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